Searchable abstracts of presentations at key conferences in endocrinology

ea0063p456 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

An investigation into the role of parathyroid hormone in the regulation of aldosterone secretion in hypertensive cardiovascular patients

Jannat Saba , Akram Maleeha , Jahan Sarwat , Kazmi Ali Raza , Afshan Kiran , Tahir Fahim , Naseem Afzaal Ahmed , Qayyum Mazhar , Rafi Muhammad , Rizvi Syed Shakeel Raza

Hypertension or elevated blood pressure (BP) is quantitatively the most important risk factor for development of cardiovascular diseases (CVDs), whereas aldosterone contributes significantly in the development and severity of hypertension. Interestingly, parathyroid hormone (PTH) stimulates aldosterone synthesis by regulating renin-angiotensin-aldosterone system (RAAS). Conversely, RAAS controls PTH secretion, as angiotensin receptor is expressed by human parathyroid tissues a...

ea0063p892 | Diabetes, Obesity and Metabolism 3 | ECE2019

An investigation into the relationship between plasma concentrations of cortisol, testosterone, blood pressure and blood glucose levels in diabetic hypersensitive cardiovascular patients

Ullah Safir , Rafi Muhammad , Akram Maleeha , Kazmi Ali Raza , Tahir Fahim , Jahan Sarwat , Afshan Kiran , Naseem Afzaal Ahmed , Qayyum Mazhar , Rizvi Syed Shakeel Raza

Diabetes mellitus type 2 (DM-2) occurs when pancreas fails to produce enough insulin or when the body cannot effectively make use of the insulin produced by the pancreas. Among other factors causing DM-2, stress is increasingly regarded as one of the causative agents that make the blood glucose levels rise, and cause DM-2. It has also been reported that DM-2 may be one of the commonest cause of hypogonadism, a lack of function in the testes, which adversely affects testosteron...

ea0063ep3 | Adrenal and Neuroendocrine Tumours | ECE2019

Depression and anxiety are positively correlated with higher concentrations of cortisol and blood pressure in hypertensive cardiovascular disease patients

Unab Shiza , Akram Maleeha , Tahir Fahim , Jahan Sarwat , Kazmi Ali Raza , Afshan Kiran , Naseem Afzaal Ahmed , Qayyum Mazhar , Rafi Muhammad , Rizvi Syed Shakeel Raza

Hypertension or high blood pressure (HBP) has been counted as the chief cause and most significant factor in the development of cardiovascular diseases (CVDs) worldwide. Stress has been defined as an inner process that happens when a person is faced with an ordinant dictation that is perceived to go beyond the resources available to efficaciously respond to it. Cortisol is a hormone released from the zona fasciculata of the adrenal cortex during the times of stress. This biolo...

ea0063p1160 | Thyroid 3 | ECE2019

Stress induced cortisol release depresses the secretion of triiodothyronine in patients with anterior wall myocardial infarction

Javid Muhammad , Kayani Amjad Rashid , Akram Maleeha , Kazmi Ali Raza , Jahan Sarwat , Afshan Kiran , Rauf Sania , Naseem Afzaal Ahmed , Tahir Fahim , Qayyum Mazhar , Rafi Muhammad , Rizvi Syed Shakeel Raza

Stress is any uncomfortable emotional experience accompanied by predictable psychological, physiological and behavioral changes. A sudden and severe stress generally produces an increase in the heart rate and blood pressure and induces a state of alertness in an individual. Evidence indicates that chronic stress depresses thyroid function, resulting in low levels of T3 and T4, which affects cardiomyocytes’ function and leads to development of cardiov...